Metabolic cofactor supplied for cellular energy and redox-pathway research.
- Dose
- 500 mg
- Batch
- 268016
NAD+
β-Nicotinamide adenine dinucleotide, oxidized form (NAD+; Coenzyme I; diphosphopyridine nucleotide, DPN; nadide)
For research purposes only — This compound is not FDA approved. All data presented is from clinical trials for educational reference.
Metabolic cofactor supplied for cellular energy and redox-pathway research.
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- Lab
- Janoshik Analytical
- Measured
- 497.73 mg
- Methods
- HPLC · LC-MS
- Tested
- Sep 15, 2026
For laboratory research use only. Not for human consumption.
Technical specifications
- Type
- Metabolic cofactor
- Scientific name
- β-Nicotinamide adenine dinucleotide, oxidized form (NAD+; Coenzyme I; diphosphopyridine nucleotide, DPN; nadide)
- Molecular weight
- 663.4 g/mol (monoisotopic 663.10912 Da)
- Formula
- C21H27N7O14P2
- CAS
- 53-84-9
- Origin
- Dinucleotide redox cofactor — adenosine monophosphate joined by pyrophosphate to nicotinamide riboside — biosynthesized in all living cells de novo from tryptophan or salvaged from niacin/nicotinamide/nicotinamide riboside.
- Lyophilized (powder)
- -20°C, desiccated and protected from light · stable long-term
- Reconstituted
- 2-8°C · aqueous NAD+ hydrolyses steadily; use within ~7 days, or aliquot and hold at -20°C to avoid freeze-thaw cycles
- Room temperature
- Powder is hygroscopic and tolerates brief shipping excursions, but solutions degrade within hours to days and NAD+ is notably alkali-labile — decomposition accelerates sharply above neutral pH. Do not store solutions at ambient temperature.
Peer-reviewed research
Published research and registered trials involving this compound. Provided for educational reference only — none of it is a claim about this product.
- Cell MetabolismTherapeutic Potential of NAD-Boosting Molecules: The In Vivo EvidenceRajman L, Chwalek K, Sinclair DA2018DOI: 10.1016/j.cmet.2018.02.011PMID: 29514064
- Nature Reviews Molecular Cell BiologyNAD+ metabolism and its roles in cellular processes during ageingCovarrubias AJ, Perrone R, Grozio A, Verdin E2021DOI: 10.1038/s41580-020-00313-xPMID: 33353981
- CellDeclining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during agingGomes AP, Price NL, Ling AJY, Moslehi JJ, Montgomery MK, Rajman L, White JP, Teodoro JS, Wrann CD, Hubbard BP, Mercken EM, Palmeira CM, de Cabo R, Rolo AP, Turner N, Bell EL, Sinclair DA2013DOI: 10.1016/j.cell.2013.11.037PMID: 24360282
- ScienceNAD+ repletion improves mitochondrial and stem cell function and enhances life span in miceZhang H, Ryu D, Wu Y, Gariani K, Wang X, Luan P, D'Amico D, Ropelle ER, Lutolf MP, Aebersold R, Schoonjans K, Menzies KJ, Auwerx J2016DOI: 10.1126/science.aaf2693PMID: 27127236
- Frontiers in Aging NeuroscienceA Pilot Study Investigating Changes in the Human Plasma and Urine NAD+ Metabolome During a 6 Hour Intravenous Infusion of NAD+Grant R, Berg J, Mestayer R, Braidy N, Bennett J, Broom S, Watson J2019DOI: 10.3389/fnagi.2019.00257PMID: 31572171
- Nature CommunicationsChronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adultsMartens CR, Denman BA, Mazzo MR, Armstrong ML, Reisdorph N, McQueen MB, Chonchol M, Seals DR2018DOI: 10.1038/s41467-018-03421-7PMID: 29599478
- Nature CommunicationsNicotinamide riboside is uniquely and orally bioavailable in mice and humansTrammell SAJ, Schmidt MS, Weidemann BJ, Redpath P, Jaksch F, Dellinger RW, Li Z, Abel ED, Migaud ME, Brenner C2016DOI: 10.1038/ncomms12948PMID: 27721479
- Ageing Research ReviewsNAD+ supplementation for anti-aging and wellness: A PRISMA-guided systematic review of preclinical and clinical evidenceGallagher C, Emmanuel OO2026DOI: 10.1016/j.arr.2026.103057PMID: 41655607
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