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CJC-1295 (No DAC)

Growth-hormone secretagogue research peptide for controlled laboratory studies.

Dose
10 mg
Batch
268012

CJC-1295 (No DAC)

[D-Ala2, Gln8, Ala15, Leu27]-human growth hormone-releasing factor (1-29) amide (tetrasubstituted hGRF(1-29)-NH2; Modified GRF 1-29)

4.9 · 214 researcher reviews

For research purposes only — This compound is not FDA approved. All data presented is from clinical trials for educational reference.

Growth-hormone secretagogue research peptide for controlled laboratory studies.

€9010 mg / vial

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Batch tested
HPLC + LC-MS
Same-day
Dispatch · 1–3 business days
COA included
Batch-traceable
Order quantity

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Certificate of Analysis · 268012On fileEU lab
Lab
Janoshik Analytical
Methods
HPLC · LC-MS
1 test on fileBatch record →

For laboratory research use only. Not for human consumption.

Compound information

Technical specifications

Molecular profile · CJC-1295 (No DAC)
Type
Peptide
Scientific name
[D-Ala2, Gln8, Ala15, Leu27]-human growth hormone-releasing factor (1-29) amide (tetrasubstituted hGRF(1-29)-NH2; Modified GRF 1-29)
Amino acids
29
Sequence
YADAIFTQSYRKVLAQLSARKLLQDILSR
Molecular weight
3367.9 g/mol
Formula
C152H252N44O42
Origin
Synthetic analog of human GHRH(1-29) bearing four substitutions (D-Ala2, Gln8, Ala15, Leu27) and a C-terminal amide — the CJC-1295 peptide backbone without the maleimidopropionyl-Lys30 drug-affinity complex. Note: residue 2 is D-alanine, which the one-letter sequence cannot express.
Storage requirements
Lyophilized (powder)
-20°C · stable long-term; keep sealed, desiccated and protected from light
Reconstituted
2-8°C · use within 30 days; aliquot to avoid repeated freeze-thaw cycles
Room temperature
Lyophilized powder tolerates short ambient excursions in transit, but the peptide is hygroscopic and prolonged ambient storage promotes moisture uptake and aggregation. In solution at room temperature it degrades by hydrolysis within days and should not be held beyond 24 hours.
Sources & references

Peer-reviewed research

Published research and registered trials involving this compound. Provided for educational reference only — none of it is a claim about this product.

  • Endocrinology
    Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog
    Jetté L, Léger R, Thibaudeau K, Benquet C, Robitaille M, Pellerin I, Paradis V, van Wyk P, Pham K, Bridon DP
    2005DOI: 10.1210/en.2004-1286PMID: 15817669
    View source →
  • Peptides
    Growth hormone responses to growth hormone-releasing hormone (1-29)-NH2 and a D-Ala2 analog in normal men
    Barron JL, Coy DH, Millar RP
    1985DOI: 10.1016/0196-9781(85)90124-xPMID: 2866496
    View source →
  • Journal of Clinical Endocrinology & Metabolism
    Incorporation of D-Ala2 in growth hormone-releasing hormone-(1-29)-NH2 increases the half-life and decreases metabolic clearance in normal men
    Soule S, King JA, Millar RP
    1994DOI: 10.1210/jcem.79.4.7962295PMID: 7962295
    View source →
  • Journal of Clinical Endocrinology & Metabolism
    Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults
    Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA
    2006DOI: 10.1210/jc.2005-1536PMID: 16352683
    View source →
  • Journal of Clinical Endocrinology & Metabolism
    Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog
    Ionescu M, Frohman LA
    2006DOI: 10.1210/jc.2006-1702PMID: 17018654
    View source →
  • American Journal of Physiology - Endocrinology and Metabolism
    Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse
    Alba M, Fintini D, Sagazio A, Lawrence B, Castaigne JP, Frohman LA, Salvatori R
    2006DOI: 10.1152/ajpendo.00201.2006PMID: 16822960
    View source →
  • Growth Hormone and IGF Research
    Activation of the GH/IGF-1 axis by CJC-1295, a long-acting GHRH analog, results in serum protein profile changes in normal adult subjects
    Sackmann-Sala L, Ding J, Frohman LA, Kopchick JJ
    2009DOI: 10.1016/j.ghir.2009.03.001PMID: 19386527
    View source →
  • Drug Testing and Analysis
    A method for confirming CJC-1295 abuse in equine plasma samples by LC-MS/MS
    Timms M, Ganio K, Steel R
    2019DOI: 10.1002/dta.2599PMID: 30938069
    View source →

Researcher reviews

Purity is exactly as stated
“99%+ is not marketing here — the LC-MS trace is on the product page. Rare to see a supplier publish the actual chromatogram.”
✓L. Petrov · Verified researcher

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