Tripeptide research compound for controlled signalling-pathway studies.
- Dose
- 10 mg
- Batch
- 268021
KPV
L-Lysyl-L-prolyl-L-valine (α-MSH 11–13), the C-terminal tripeptide of α-melanocyte-stimulating hormone · KPV
For research purposes only — This compound is not FDA approved. All data presented is from clinical trials for educational reference.
Tripeptide research compound for controlled signalling-pathway studies.
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- Lab
- Freedom Diagnostics
- Purity
- 99.97%
- Methods
- HPLC-UV · LC-MS
- Tested
- Sep 25, 2026
For laboratory research use only. Not for human consumption.
Technical specifications
- Type
- Peptide
- Scientific name
- L-Lysyl-L-prolyl-L-valine (α-MSH 11–13), the C-terminal tripeptide of α-melanocyte-stimulating hormone
- Amino acids
- 3
- Sequence
- KPV
- Molecular weight
- 342.43 g/mol
- Formula
- C16H30N4O4
- CAS
- 67727-97-3
- Origin
- C-terminal tripeptide (residues 11–13) of α-melanocyte-stimulating hormone (α-MSH); verified as PubChem CID 125672.
- Lyophilized (powder)
- -20°C · stable long-term; protect from light and moisture
- Reconstituted
- 2-8°C · use within 30 days in sterile solvent
- Room temperature
- Lyophilized powder tolerates brief ambient shipping excursions, but reconstituted solution held at room temperature degrades by peptide-bond hydrolysis and is subject to microbial growth — refrigerate after reconstitution rather than storing at ambient temperature.
Peer-reviewed research
Published research and registered trials involving this compound. Provided for educational reference only — none of it is a claim about this product.
- The FASEB JournalAntiinflammatory activity of a COOH-terminal fragment of the neuropeptide alpha-MSHHiltz ME, Lipton JM1989PMID: 2550304
- Journal of Leukocyte BiologyAntimicrobial effects of alpha-MSH peptidesCutuli M, Cristiani S, Lipton JM, Catania A2000DOI: 10.1002/jlb.67.2.233PMID: 10670585
- Journal of Pharmacology and Experimental TherapeuticsDissection of the anti-inflammatory effect of the core and C-terminal (KPV) alpha-melanocyte-stimulating hormone peptidesGetting SJ, Schiöth HB, Perretti M2003DOI: 10.1124/jpet.103.051623PMID: 12750433
- Journal of Investigative Dermatologyalpha-Melanocyte-stimulating hormone, MSH 11-13 KPV and adrenocorticotropic hormone signalling in human keratinocyte cellsElliott RJ, Szabo M, Wagner MJ, Kemp EH, MacNeil S, Haycock JW2004DOI: 10.1111/j.0022-202X.2004.22404.xPMID: 15102092
- GastroenterologyPepT1-mediated tripeptide KPV uptake reduces intestinal inflammationDalmasso G, Charrier-Hisamuddin L, Nguyen HT, Yan Y, Sitaraman S, Merlin D2008DOI: 10.1053/j.gastro.2007.10.026PMID: 18061177
- Inflammatory Bowel DiseasesMelanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel diseaseKannengiesser K, Maaser C, Heidemann J, Luegering A, Ross M, Brzoska T, Bohm M, Luger TA, Domschke W, Kucharzik T2008DOI: 10.1002/ibd.20334PMID: 18092346
- Molecular TherapyOrally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative ColitisXiao B, Xu Z, Viennois E, Zhang Y, Zhang Z, Zhang M, Han MK, Kang Y, Merlin D2017DOI: 10.1016/j.ymthe.2016.11.020PMID: 28143741
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